Bird Flu - Avian Flu - Avian Influenza A H5N1 Virus



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Avian Flu Vaccine

Vaccine a Powerful Weapon

The most important tool for fighting the ever-changing flu virus is immunization by a killed-virus vaccine licensed by FDA.

Currently no vaccine is available to protect humans against the H5N1 virus that is being seen in Asia. However, bird flu vaccine development efforts are under way. Research studies to test a vaccine to protect humans against H5N1 virus began in April 2005. (Researchers are also working on a vaccine against H9N2, another bird flu virus subtype.)

Prescription antiviral oseltamivir (Tamiflu) and the a lesser extent zanamivir (Relenza) are the only medications that are effective against avian flu. The drugs can prevent infection up to 80 percent and can treat patients who have had symptoms for 2 days or less. However, flu viruses can become resistant to these drugs, so these medications may not always work.

Flu is a highly contagious disease, spreading mostly by direct person-to-person contact. With the flu, coughing--even more than sneezing--is the leading cause of flu transmission.

The flu virus can linger in the air for as long as three hours. In close quarters, conditions are ripe for the spread of the virus.

The challenge for scientists trying to protect us from the disease is that influenza viruses can change themselves, or mutate, to become different viruses. Scientists have classified flu viruses as types A, B and C.
Type A is the most common and leads to the most serious epidemics.
Type B can cause epidemics, but usually produces a milder disease than type A. Type C viruses have never been associated with a large epidemic. The bird flu or Avian flu is a Type A virus, hence Avian influenza 'A' H5N1.

In the not-too-distant future, consumers may have alternatives to the flu shot, including different delivery methods like nasal drops or a spray. Major pharmaceutical companies, are making significant strides, also, toward an even more protective vaccine.

In the rare cases when the vaccine is not advisable, two prescription drugs are available for prevention of type A influenza: Symmetrel (amantadine), approved by FDA in 1976, and Flumadine (rimantadine), approved by FDA in 1993. Either drug also can be used to reduce symptoms and shorten the illness if administered within 48 hours after symptoms appear. However, neither of these has documented effectiveness treating Avian A H5N1 virus or bird flu virus.

 
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